NURS 6521 QUIZ 1
Question 1
1 out of 1 points
In which of the following patients would a nurse expect to experience alterations in
drug metabolism?
Response
Feedback:
The liver is the most important site for dru
...
NURS 6521 QUIZ 1
Question 1
1 out of 1 points
In which of the following patients would a nurse expect to experience alterations in
drug metabolism?
Response
Feedback:
The liver is the most important site for drug metabolism. If the liver is
not functioning effectively, as with cirrhosis, drugs will not be
metabolized normally and toxic levels could develop. Drug dosage will
have to be altered to ensure normal levels in the body. The patient
with kidney stones and the patient in acute renal failure would most
likely have alterations in drug excretion. If there are no complications
with the cervical cancer patient, there should be no alterations in drug
therapy.
Question 2
1 out of 1 points
The nurse's assessment of a community-dwelling adult suggests that the client may
have drug allergies that have not been previously documented. What statement by
the client would confirm this?
Response
Feedback:
True allergic reactions include formation of rash or hives, itching,
redness, swelling, difficulty breathing, and anaphylactic shock.
Nausea and vomiting, however, are adverse effects of drug therapy.
Similarly, an unsafe drop in blood pressure and gastric bleeding from
aspirin use are adverse drug effects, not allergic reactions.
Question 3
0 out of 1 points
A patient who has ongoing pain issues has been prescribed meperidine (Demerol)
IM. How should the nurse best administer this medication?
Response
Feedback:
The ventrogluteal site is the preferred site for intramuscular injection.
IM injections necessitate the use of a larger gauge needle than is
required for subcutaneous injections.
Question 4
1 out of 1 points
A patient with a variety of chronic health problems is being seen by her nurse
practitioner, who is currently reviewing the patient's medication regimen. Which of
the patient's medications should prompt the nurse to teach her to avoid drinking
grapefruit juice?Response
Feedback:
Metabolism of many varied drugs such as calcium channel blockers
(used to treat hypertension), statins (used to lower blood lipid levels),
and antihistamines (used to prevent allergic reactions) is affected by
grapefruit juice.
Question 5
1 out of 1 points
A nurse is discussing with a patient the efficacy of a drug that his physician has
suggested, and he begin taking. Efficacy of a drug means which of the following?
Response
Feedback:
Efficacy indicates how well a drug produces its desired effect.
Different drugs have different strengths of attraction or affinity for
receptor sites. A drug's ability to stimulate its receptor is called its
intrinsic activity, and the amount of a drug that must be given to
produce a particular response is called the potency of a drug.
Question 6
1 out of 1 points
A home health nurse notes that there have been changes to a patient's oral drug
regimen. The nurse will closely monitor the new drug regimen to
Response
Feedback:
Changes in the drug regimen may cause changes in drug absorption
and thereby decrease the anticipated drug effect. This decrease is
due to the prevention of binding and loss of absorption and overall
drug effectiveness. A change in the drug regimen would not help a
nurse to track the route of metabolism or determine the speed of
chelation. If any adverse effect were to occur as a result of a drug
regimen change, it would not necessarily be immunotoxicity; it could
also be nephrotoxicity, ototoxicity, or cardiotoxicity.
Question 7
1 out of 1 points
5 ml = _______________tsp
Question 8
1 out of 1 points
A nurse is caring for a patient who has had part of her small intestine removed due
to cancer. She has also now developed hypertension and has been prescribed a
new medication to decrease her blood pressure. While planning the patient's care,
the nurse should consider a possible alteration in which of the following aspects of
pharmacokinetics?Response
Feedback:
Because absorption takes place mostly in the small intestine, there
could be possible alterations with this process. Distribution takes
place in the blood vessels; metabolism in the liver; and elimination via
the kidneys. Because these systems are not affected by her surgery,
these phases of pharmacokinetics would not be altered.
Question 9
1 out of 1 points
A patient has a blood serum drug level of 50 units/mL. The drug's half-life is 1 hour.
If concentrations above 25 units/mL are toxic and no more of the drug is given, how
long will it take for the blood level to reach the nontoxic range?
Response
Feedback:
Half-life is the time required for the serum concentration of a drug to
decrease by 50%. After 1 hour, the serum concentration would be 25
units/mL (50/2). After 2 hours the serum concentration would be 12.5
units/mL (25/2) and reach the nontoxic range.
Question 10
1 out of 1 points
A patient with a recent diagnosis of acute renal failure has a long-standing seizure
disorder which has been successfully controlled for several years with antiseizure
medications. The nurse should recognize that the patient's compromised renal
function will likely
Response
Feedback:
Impaired renal function will increase the half-life of drugs that are
metabolized by the kidneys. This does not necessarily render such
medications ineffective and it does not decrease the first-pass effect.
IV administration will not compensate for the patient's impaired renal
function.
Question 11
1 out of 1 points
A nurse is caring for a patient who has recently moved from Vermont to south
Florida. The patient has been on the same antihypertensive drug for 6 years and has
had stable blood pressures and no adverse effects. Since her move, however, she
reports “dizzy spells and weakness” and feels that the drug is no longer effective.
The nurse suspects that the change in the effectiveness of the drug is related to
Response
Feedback:
Antihypertensive drugs work to decrease blood pressure. When a
patient goes to a climate that is much warmer than usual, blood
vessels dilate and the blood pressure decreases. If a patient is taking
an antihypertensive drug and enters a warmer climate, there is a
chance that the patient's blood pressure will drop too low, resulting in
dizziness and a feeling of weakness. After several years on anantihypertensive drug, the effects of that drug are known; therefore,
the placebo effect should not be an issue. Most antihypertensives are
metabolized and excreted and do not accumulate in the body. The
patient has not given the nurse any information that would indicate
that she has not been compliant with her drug regimen due to the
move.
Question 12
1 out of 1 points
A 56-year-old female patient has been admitted to the hospital with chronic muscle
spasms and has been prescribed a new medication to treat the spasms. She has a
poorly documented allergy to eggs, synthetic clothes, and perfumes. What is the
priority action of the nurse to ensure that prescribed medication does not experience
an allergic reaction?
Response
Feedback:
The nurse should post an allergies notice on the front of the chart and
document the allergies in the appropriate area of the patient's record;
this will allow continuous access of the dietary staff and the other
members of the health care team to the information and serve to limit
errors. The prescriber would always ask the patient about her
allergies before prescribing a new medication. The patient is not
having an allergic reaction, so treating her for an allergic reaction is
unnecessary. If the allergies are documented in the appropriate area
of the patient's record, the dietary staff will be aware that the patient
should not be served eggs.
Question 13
1 out of 1 points
In order to promote therapeutic drug effects, the nurse should always encourage
patients to
Response
Feedback:
Taking a drug at the appropriate time will help the patient maintain
therapeutic drug levels. Not all medications should be taken with
food, which can alter the absorption of some drugs. A patient should
never increase or decrease a medication dosage without checking
with the prescriber. Alternative therapy should only be used if the
patient has discussed the therapy with the prescriber and they are in
agreement.
Question 14
1 out of 1 points
Talwin given in combination with Vistaril diminishes the adverse effects of nausea
caused by the Talwin. This drug interaction affecting the pharmacodynamics of the
Talwin isResponse
Feedback:
An antagonistic drug interaction results in a therapeutic effect that is
less than the effect of either drug alone because the second drug
either diminishes or cancels the effects of the first drug. An additive
effect occurs when two or more “like” drugs are combined and the
result is the sum of the drugs' effects. A synergistic effect occurs
when two or more “unlike” drugs are used together to produce a
combined effect and the outcome is a drug effect greater than either
drug's activity alone. Potentiation is an interaction in which the effect
of only one of the two drugs is increased.
Question 15
1 out of 1 points
An older adult patient with a history of Alzheimer's disease and numerous chronic
health problems has been prescribed several medications during his current
admission to hospital and recent declines in the patient's cognition have impaired his
ability to swallow pills. Which of the following medications may the nurse crush
before administering them to this patient?
Response
Feedback:
A tablet that is designed for immediate release into the gastric
environment is normally safe to crush and administer to the patient.
Enteric coated and sustained release tablets may not be crushed
because doing so compromising the delayed release into the GI tract
that is intended with these medications. Sublingual medications
should be placed under the tongue to dissolve rather than swallowed.
Question 16
1 out of 1 points
A patient is treated with an antibiotic for an infection in his leg. After 2 days of taking
the antibiotic, the patient calls the clinic and reports that he has a rash all over his
body. The nurse is aware that a rash can be an adverse effect of an antibiotic and
can be either a biologic, chemical, or physiologic action of the drug, which is an
example of
Response
Feedback:
Pharmacodynamics is the biologic, chemical, and physiologic actions
of a particular drug within the body and the study of how those actions
occur, including adverse effects. It is how the drug affects the body.
The pharmacodynamics of a drug is responsible for its therapeutic
effects and sometimes its adverse effects. Pharmacotherapeutics
refers to the desired, therapeutic effect of the drug. Pharmacokinetics
is the changes that occur to the drug while it is inside the body.
Pharmacogenetics is the study of how genetic variables affect the
pharmacodynamics of a drug in a specific patient.
Question 17
1 out of 1 pointsA patient has been prescribed several drugs and fluids to be given intravenously.
Before the nurse starts the intravenous administration, a priority assessment of the
patient will be to note the
Response
Feedback:
Baseline body weight and height, heart rate, and blood pressure are
all important considerations during the assessment of a patient.
However, if a patient has to be given drugs intravenously, it is
important to inspect the skin for rashes, moles, or sores, so those
areas can be avoided as an insertion or injection site.
Question 18
1 out of 1 points
For which of the following patients would a nasogastric tube most likely be
considered to aid in the administration of medications?
Response
Feedback:
The use of an NG tube for medication administration requires a
functioning GI tract. An NG tube would not be used if a patient is
vomiting frequently or has had recent bowel surgery. Similarly, an NG
tube would not be used in the case of a competent adult who wishes
to discontinue his or her medications.
Question 19
1 out of 1 points
An elderly postsurgical patient has developed postoperative pneumonia in the days
following abdominal surgery and is being treated with a number of medications.
Which of the following medications that the nurse will administer has the slowest
absorption?
Response
Feedback:
Absorption of drugs is dependent primarily on the route of
administration. IV, IM, and sublingual administration results in faster
absorption than drugs that are given orally.
Question 20
1 out of 1 points
An unconscious patient has been brought to the hospital, and the physician has
prescribed a life-saving drug to be administered parenterally. Which of the following
methods would be the most appropriate for the nurse to use when administering the
medication?
Response
Feedback:
Intravenous infusion is the preferred method for use in emergency
situations when rapid drug effects are desired. Absorption is
considered to be instantaneous, as the drug is placed directly into the
bloodstream. The subcutaneous and intramuscular routes could be
used but would not ensure rapid drug effects. Intrathecaladministration is usually done by a physician or a specially trained
health care provider.
Question 21
1 out of 1 points
Which of the following statements best defines how a chemical becomes termed a
drug?
Response
Feedback:
Even though all the responses are correct, a chemical must undergo
a series of tests to determine its therapeutic value and efficacy
without severe toxicity or damaging properties before it is termed a
drug. Test results are reported to the FDA, which may or may not
give approval.
Question 22
1 out of 1 points
A nurse is instructing a patient concerning a newly prescribed drug. Which of the
following should be included to help improve patient compliance and safety?
Response
Feedback:
If patients are aware of certain adverse effects and how to alleviate or
decrease the discomfort, they are more likely to continue taking the
medication and providing for safe administration. A list of pharmacies
can be useful information, but will not improve safety or compliance.
Knowing the cost of the brand versus the generic could also be
helpful to the patient. However, a substitution may not be allowed,
and the cost of a drug does not improve patient safety. Most patients
are not concerned with statistics regarding drug testing, and the
testing is usually not discussed with patients.
Question 23
1 out of 1 points
A patient has been receiving regular doses of an agonist for 2 weeks. Which of the
following should the nurse anticipate?
Response
Feedback:
Receptors are not static; they can change or modify their response to
a stimulus. Such change occurs when a receptor is continuously
stimulated to act or continually inhibited from action. Continual
stimulation from an agonist usually makes the receptor desensitized
to the drug and thus less active. Therefore, the nurse should
anticipate a decrease in effectiveness of the drug.
Question 24
1 out of 1 points
During a clinic visit, a patient complains of having frequent muscle cramps in herlegs. The nurse's assessment reveals that the patient has been taking over-thecounter laxatives for the past 7 years. The nurse informed the patient that prolonged
use of laxatives
Response
Feedback:
Long-term intake of laxatives, antidepressants, and antibiotics has
been found to deprive a person of most essential nutrients, such as
vitamins. Prolonged use of laxatives is not known to turn urine acidic,
cause urinary tract infections, counter the effect of other drugs, or
inhibit the biotransformation of drugs.
Question 25
1 out of 1 points
The nurse is caring for a patient receiving an aminoglycoside (antibiotic) that can be
nephrotoxic. Which of the following will alert the nurse that the patient may be
experiencing nephrotoxicity?
Response
Feedback:
Decreased urinary output, elevated blood urea nitrogen, increased
serum creatinine, altered acid–base balance, and electrolyte
imbalances can occur with nephrotoxicity. Ringing noise in the ears
(tinnitus) is an indication of possible ototoxicity. Visual disturbances
can suggest neurotoxicity, and yellowing of the skin (jaundice) is a
sign of hepatotoxicity.
Question 26
1 out of 1 points
A 72-year-old man who is unable to sleep since admission into the hospital is given
a hypnotic medication at 9 p.m. The nurse finds the patient drowsy and confused at
10 a.m. the next day. The nurse is aware that this behavior is most likely due to
Response
Feedback:
Decreased hepatic function may extend the half-life of a drug and
increase the patient's response to the drug. Increased renal function
would rid the body of the drug faster than normal and would not
cause prolonged effects. A toxic effect would be a more serious effect
such as inability to awaken the patient. An allergic reaction does not
usually manifest itself as a confused and drowsy state.
Question 27
1 out of 1 points
A 70-year-old man with diabetes mellitus is taking metoprolol (Lopressor) to manage
his hypertension. The nurse would be sure to instruct the patient to
Response
Feedback:
Beta-adrenergic antagonists should be used cautiously in patients
with diabetes mellitus because beta blockade can mask the signs of
hypoglycemia, especially palpitations, tachycardia, and tremors.Taking his pulse, weekly weighing, and avoiding smoke-filled rooms
are good health practices and should be done when taking these
drugs, but they are not specifically necessary for a diabetic patient
taking a beta-adrenergic antagonist.
Question 28
1 out of 1 points
A 70-year-old patient has just started taking lorazepam 10 days ago for anxiety
issues related the death of her husband. She is staying with her daughter for a
couple of weeks. The patient's daughter has noticed that her mother is having
difficulty walking and seems to be confused at times and calls the clinic to report this
to the nurse. The nurse will inform the daughter that
Response
Feedback:
If ataxia and confusion occur, especially in older adults or in a
debilitated patient, dose adjustments should be made if the effects
persist. If the drug is stopped immediately, withdrawal symptoms may
occur. Intravenous administration or continuing the same dosage and
medication would not help relieve ataxia or confusion in the patient.
Question 29
1 out of 1 points
A nurse is teaching an older adult patient about polypharmacy. Which of the
following statements best describe this term?
Response
Feedback:
Polypharmacy is defined as taking several drugs at the same time.
The other options are false statements.
Question 30
1 out of 1 points
A 79-year-old woman with a medical history that includes osteoporosis has recently
moved to a long-term care facility. Medication reconciliation indicates that the
woman has been taking calcitonin, salmon for several years. The nurse should
recognize that the most likely route for the administration of this drug is
Response
Feedback:
For postmenopausal osteoporosis, the recommended intranasal dose
of calcitonin is 200 international units, in alternating nostrils each day.
This practice decreases nasal irritation. Intranasal administration is
preferred over IM, SC, or IV routes.
Question 31
1 out of 1 points
A 70-year-old man who enjoys good health began taking low-dose aspirin several
months ago based on recommendations that he read in a magazine article. During
the man's most recent visit to his care provider, routine blood work was ordered andthe results indicated an unprecedented rise in the man's serum creatinine and blood
urea nitrogen (BUN) levels. How should a nurse best interpret these findings?
Response
Feedback:
Damage to the kidneys is called nephrotoxicity. Decreased urinary
output, elevated blood urea nitrogen, increased serum creatinine,
altered acid-base balance, and electrolyte imbalances can all occur
with kidney damage.
Question 32
1 out of 1 points
A nurse is administering drugs to a 70-year-old patient who has a reduced plasma
albumin level. When assessing the patient for therapeutic outcomes of drug therapy,
the nurse will also be careful to observe for
Response
Feedback:
Decreased levels of plasma albumin can lead to fewer binding sites
for protein-binding drug molecules. Decreased binding sites results in
higher concentrations of unbound forms of a drug, which increases
the risk of adverse effects and toxicity and can increase therapeutic
effects. Plasma albumin does not alter absorption of a drug but is
responsible for binding, transporting, and distributing drugs
throughout the body. Even though higher concentrations of a free
drug increase the amount of the drug available for metabolism,
normal age-related decreases in liver function offset any increase in
the pharmacokinetic process.
Question 33
1 out of 1 points
A 70-year-old woman has experienced peripheral edema and decreasing stamina in
recent months and has sought care from her primary care provider. The patient's
subsequent diagnostic workup has resulted in a diagnosis of chronic heart failure.
The woman has been prescribed digoxin and the nurse has begun patient education.
What should the nurse teach the patient about her new medication?
Response
Feedback:
Digoxin is used to maintain clinical stability and improve symptoms,
quality of life, and exercise tolerance in patients with all phases of
CHF; it does not decrease mortality from CHF or cure the disease.
Digoxin increases urine production but its therapeutic effect is not
primarily gained from diuresis or blood pressure reduction.
Question 34
1 out of 1 points
A nurse who is working with an older adult patient who takes eight medications a day
wants to promote medication adherence. Which of the following nursing
interventions would best promote medication adherence?Response
Feedback:
Placing pills in a daily or weekly pillbox will help remind the patient to
take the pills as scheduled and should serve as a visual aid to help
make him more aware of having to take medication. Patients should
always take medications as prescribed to ensure therapeutic effects,
and prescriptions should be refilled prior to the last dose to ensure
continuity of drug therapy. Elderly patients should ask for bottles with
easy open caps due to possible arthritic changes that might interfere
with the patient opening a bottle.
Question 35
1 out of 1 points
Mr. Penny, age 67, was diagnosed with chronic angina several months ago and has
been unable to experience adequate relief of his symptoms. As a result, his
physician has prescribed ranolazine (Ranexa). Which of the following statements is
true regarding the use of ranolazine for the treatment of this patient's angina?
Response
Feedback:
Ranolazine should be used only in combination with other antianginal
therapy (either nitrates, beta blockers (metoprolol or atenolol), or
amlodipine, a calcium channel blocker. It does not achieve its effects
by lowering the heart rate or the blood pressure. Ranolazine has the
potential to prevent MI.
Question 36
1 out of 1 points
A nurse who provides care for older adults is aware of the high incidence of drug
interactions in this population. When educating a group of seniors about the
prevention of drug interactions, the nurse should encourage them to
Response
Feedback:
The introduction of new drugs into an individual's drug regimen
without the advice of a health professional can increase the risk of
drug interactions. This measure is more important that taking all drugs
with food or taking drugs individually since these actions do not
remove the risk of adverse drug interactions. A healthy lifestyle is of
benefit to older adults, but does not mitigate the potential for drug
interactions.
Question 37
1 out of 1 points
Medication reconciliation of an 82-year-old man who has recently moved to a longterm care facility reveals that the man takes 1 to 2 mg of lorazepam bid prn. The
nurse should recognize what consequence of this aspect of the resident's drug
regimen?
Response In a systematic review of medications as risk factors for fall, it wasFeedback: found that one of the main group of drugs associated with this risk
were benzodiazepines. Benzodiazepines are not associated with cold
intolerance, anorexia, or aggression.
Question 38
1 out of 1 points
An older adult who lives in a long-term care facility has recently begun taking
losartan (Cozaar) for the treatment of hypertension. The nurse who provides care for
this resident should recognize that this change in the resident's medication regimen
make create a risk for
Response
Feedback:
Angiotensin II receptor blockers such as losartan are associated with
a risk of dizziness and a consequent risk for falls. This risk is more
pronounced among older adults. Losartan is not associated with
constipation, xerostomia, or depression.
Question 39
1 out of 1 points
Frequent episodes of exercise-related chest pain have caused a 79-year-old woman
to use her prescribed nitroglycerin spray several times in recent weeks. This
patient's age will have what effect on her use of nitroglycerin?
Response
Feedback:
Older adults may have a more pronounced venous dilation from
nitroglycerin than younger adults and may experience more
hypotension from the drug. Xerostomia does not inhibit the absorption
of nitroglycerin spray and it is unnecessary to adjust the timing of
nitroglycerin doses based on age.
Question 40
1 out of 1 points
An elderly man has been admitted to a residential care facility and the nurse has
conducted a medication reconciliation. The man has taken numerous drugs in the
past, including a course of bicalutamide (Casodex) several years earlier. The nurse
recognizes this drug as being an antiandrogen and is consequently justified in
presuming that the man has a history of what disease?
Response
Feedback:
In male patients, antiandrogens are used to treat prostate cancer.
They are not included in treatment of lymphomas, skin cancer, or
lung cancer.
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