Lecture 1— Acid-Base Balance
Ventilators
Lecture 2— Alcohol
Wernicke
Overdose and Withdrawal
S/Sx
Aminoglycosides
Peak and Trough
Lecture 3— Drug Toxicities (Lithium,
Lanoxin, Dilantin, Bilirubin,
Aminophylline
...
Lecture 1— Acid-Base Balance
Ventilators
Lecture 2— Alcohol
Wernicke
Overdose and Withdrawal
S/Sx
Aminoglycosides
Peak and Trough
Lecture 3— Drug Toxicities (Lithium,
Lanoxin, Dilantin, Bilirubin,
Aminophylline)
Kernicterus
Dumping/HH
Electrolytes: K+, CA, MG,
and NA
TX for HyperKalemia
Lecture 4— Crutches
Canes
Walkers
Delusions
Hallucinations
Psychosis
Psychotic and Non-Psychotic
Hallucination
Illusion
Delusion
Lecture 5— Diabetes Mellitus
Diabetes Insipidus
SIADH
Insulin
DKA
HHNK
Lecture 6— Drug Toxicities (Lithium,
Lanoxin, Dilantin, Bilirubin,
Aminophylline)
Kernicterus
Dumping/HH
Electrolytes: K+, CA, MG,
and NA
TX for HyperKalemia
Lecture 7— Thyroid (Hyper-, Hypo-)
Adrenal Cortex (Addison
Disease, Cushing)
Toys
Laminectomy
Lecture 8— Lab Values
Five Deadly Ds
Neutropenic Precaution
Lecture 9— Psych Drugs
Tri
Benzo
MAOI
Lithium
Prozac
Haldol
Clozaril
Zoloft
Lecture 10— Maternity and Neonatology
Lecture 11— Fetal Complications
Stages of Labor
Assessments
Variations for NB
Maternity Meds
Medication Hints
Psych Tips
Operational Stages
Lecture 12— Prioritization
Delegation
Staff Management
Guessing Strategies
GUIDE • Mark Klimek’s LecturePage 2 of 92Page 3 of 92
Acid/Base Balance (Start times: 30:00)
In order to solve acid-base disorders, it is
important to know the normal values for
pH, CO2 and HCO3 (bicarbonate), which
are shown below
• pH 7.35 to 7.45
• CO2 35 to 45
• HCO3 22 to 26
The first value to look at in an acid-base
disorder is the pH
• If pH is <7.35, the acid-base imbalance
is acidotic
• If pH is <7.45, the acid-base imbalance
is alkalotic
Now, to determine if the imbalance is metabolic or respiratory, determine whether HCO3 goes
in the same or opposite direction with pH
• Rule of the Bs: If pH and Bicarb move both in the same direction, then the acid-base
imbalance is metabolic … Otherwise, it is respiratory
Example #1
• pH 7.3 Acidotic
• HCO3 20 Metabolic
• This is an example of metabolic acidosis
Example #2
• pH 7.58 Alkalotic
• HCO3 32 Metabolic
• This is an example of metabolic alkalosis
Example #3
• pH 7.22 Acidosis
• HCO3 35 Respiratory
• This is an example of respiratory acidosis
As the pH goes, so goes my patient, except for Potassium … That means
• If pH is low, everything is low, except potassium
• If pH is high, everything is high, except potassium
Lecture 1 • Mark Klimek • 92:21Page 4 of 92
If pH goes over 7.45, this is alkalosis
• Therefore everything is up: tachycardia, tachypnea, HTN, seizures, irritability, spastic,
diarrhea, borborygmi (increase bowel sounds), hyperreflexia (3+, 4+)
• However, potassium is opposite. Therefore, hypokalemia
• What is the nursing intervention?
o Pt need suctioning because of seizures
If pH goes below 7.35, this is acidosis
• Therefore, everything is down: bradycardia, constipation, absent bowel sounds, flaccid,
obtunded, lethargy, coma hyporeflexia (0, 1+), bradypnea, low BP
• However, potassium is high (hyperkalemia)
• What is the nursing intervention?
o Pt needs to be ventilated with an Ambu bag—respiratory arrest
So, remember that “MAC Kussmaul” is the only acid-base imbalance to cause Metabolic
ACidosis with Kussmaul respirations
Causes of Acid/Base imbalance
First ask yourself, “Is it LUNG? … If yes, then it is respiratory
• Then ask yourself, “Are they overventilating or underventilating?
o If UNDERventilating, then pick acidosis—pH is under 7.35
o If OVERventilating, then it is alkalosis, pH is over 7.45
What type of acid-base derangement is present in the following condition?
• In labor?
o Respiratory alkalosis … Overventilating—pH increases … Alkalosis)
• Drowning?
o Respiratory acidosis … Underventilating—pH decreases … Acidosis
• Pt is on PCA (patient-controlled anesthesia) pump?
o Ventilation is down … Respiratory acidosis
If it is not LUNG, then it is metabolic. If the patient has prolonged
gastric vomiting or suction (sucking out acid), pick alkalosis
• For everything else that isn’t lung, pick metabolic acidosis
• So, when you don’t know what to pick, pick metabolic
acidosis
Tip
• Set your default setting to Metabolic Acidosis
• Always pay attention to modifying phrase rather than original
noun
Figure 1. Patientcontrolled anesthesia
(PCA) pump.Page 5 of 92
Ventilator
A ventilator is a machine designed to move breathable air into and out of the lungs, aids patients
who are physically unable to breathe, or breathing insufficiently to breathe … A ventilators is
equipped with a high and a low-pressure alarm
High pressures alarms are
always triggered by increased
resistance to air flow. Look
for obstructions, i.e.,
• Kinks in tubing …
Solution: unkink the tube
• Condensed water in the
dependent tube …
Solution: empty it
• Mucus plugs … Solution:
Ask pt to turn, cough, deep
breathe; or suction the
tubing PRN
What is the appropriate order
to address high pressure alarm
in a mechanical ventilator?
• (1) Unkink. (2) Empty
water out of tubing. (3) turn pt, ask pt to cough or deeply breathe, and (4) suction
Low pressures alarms are always triggered by decrease in resistance. This can be caused by
• Main tubing disconnection
• O2 sensor tube disconnection
• In both cases, reconnect the disconnected tubing unless tube is on floor … Bag pt and call
Respiratory Therapist
The ventilator may be set too high or too low
• Setting is too high … Pt is overventilated
o Respiratory Alkalosis … Panting
• Setting is too low … Pt is underventilated
o Respiratory Acidosis … Pt is retaining CO2
Question
The physician wants to wean pt off vent in the morning. At 6 am, the ABGs say respiratory
acidosis. What would you do next?
• Notify the physician that the pt is not ready to be weaned off the respirator
o Pt is is respiratory acidosis, which means that he is underventilated … Therefore not ready
to be weaned off the ventilator
o If pt were in respiratory alkalosis (overventilated), he should be ready to be weaned offPage 6 of 92
Alcoholism
• The #1 psychological problem is DENIAL
• How do you respond/treat to pts in denial?
o Confront them by pointing out the difference b/w
what they say and what they do
o For instance, say something like: “Ok, you say
you’re not an alcoholic but it is 10 a.m. and you’ve
already had a 6 pack” … It is not the same as
aggression. Don’t attack the person
o Good answer has “I” … Bad answer has “YOU”
o One place where denial is ok—loss and grief
Stages of grief are “DABDA”—Denial, anger,
bargaining, depression, acceptance
o So when the question is about pt in denial, pay attention to whether you are dealing with
loss or abusive situation
Support = Loss
Confront = Abuse
Dependency vs. Co-dependency
• The #2 psychological problem is Dependency or Co-Dependency
• Dependency: when the get the significant other to do things or make decisions for them
o The abuser is dependent
• Co-dependency: when the significant other derive self-esteem for doing things or making
decisions for the abuser
o The significant other is the co-dependent
• Dependency and co-dependency has a symbiotic, yet a pathological relationship
o The dependent pt get a free ride on the co-dependent
o The co-defendant pt feels good from “doing stuff” for the abuser
• How do you treat dependency/codependency?
o Dependent pts are “abusers” … Confront them
o Co-dependent pts have self-esteem issues … Teach pts how to set limits and enforce them
o Agree in advance on what requests are allowed then enforce
o Teach significant other to say no
o Work on self-esteem on the co-dependent person
Manipulation
• Manipulation is when the abuser gets the significant other to do things or make decisions
that are not in the best interests of the significant other
o The nature of the act is dangerous and harmful to the significan
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