Pharma NR 508 Final (ASSURED A)
Chapter 16. Drugs Affecting the Cardiovascular and Renal Systems
Multiple Choice
Identify the choice that best completes the statement or answers the question.
____ 1. Ray has been dia
...
Pharma NR 508 Final (ASSURED A)
Chapter 16. Drugs Affecting the Cardiovascular and Renal Systems
Multiple Choice
Identify the choice that best completes the statement or answers the question.
____ 1. Ray has been diagnosed with hypertension and an angiotensin-converting enzyme inhibitor is
determined to be needed. Prior to prescribing this drug, the NP should assess for:
1. Hypokalemia
2. Impotence
3. Decreased renal function
4. Inability to concentrate
____ 2. Angiotensin-converting enzyme inhibitors are the drug of choice in treating hypertension in diabetic
patients because they:
1. Improve insulin sensitivity
2. Improve renal hemodynamics
3. Reduce the production of angiotensin II
4. All of the above
____ 3. A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is
angioedema. Which of the following statements is true about this adverse response?
1. Swelling of the tongue or hoarseness are the most common symptoms.
2. It appears to be related to the decrease in aldosterone production.
3. Presence of a dry, hacky cough indicates a high risk for this adverse response.
4. Because it takes time to build up a blood level, it occurs after being on the drug for
about 1 week.
____ 4. Angiotensin-converting enzyme inhibitors are useful in a variety of disorders. Which of the
following statements are true about both its usefulness in the disorder and the reason for its use?
1. Stable angina because it decreases the thickening of vascular walls due to
decreased modified release.
2. Heart failure because it reduces remodeling of injured myocardial tissues.
3. Both 1 and 2 are true and the reasons are correct.
4. Both 1 and 2 are true but the reasons are wrong.
5. Neither 1 nor 2 are true.
____ 5. Despite good blood pressure control, an NP might change a patient’s drug from an angiotensinconverting enzyme (ACE) inhibitor to an angiotensin II receptor blocker (ARB) because the ARB:
1. Is stronger than the ACE inhibitor
2. Does not produce a dry, hacky cough
3. Has no effect on the renal system
4. Reduces sodium and water retention
TestBankWorld.org
____ 6. While taking an angiotensin II receptor blocker (ARB), patients need to avoid certain over-thecounter drugs without first consulting the provider because:
1. Cimetidine is metabolized by the CYP 3A4 isoenzymes
2. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
3. Both 1 and 2
4. Neither 1 nor 2
____ 7. Laboratory monitoring for patients on angiotensin-converting enzyme inhibitors or angiotensin II
receptor blockers should include:
1. White blood cell counts with the drug dosage increased for elevations above
10,000 feet
2. Liver function tests with the drug dosage stopped for alanine aminotransferase
values twice that of normal
3. Serum creatinine levels with the drug dosage reduced for values greater than 2.5
mg/dL
4. Serum glucose levels with the drug dosage increased for levels greater than 120
mg/dL
____ 8. Jacob has hypertension, for which a calcium channel blocker has been prescribed. This drug helps
control blood pressure because it:
1. Decreases the amount of calcium inside the cell
2. Reduces stroke volume
3. Increases the activity of the Na+/K+/ATPase pump indirectly
4. Decreases heart rate
____ 9. Which of the following adverse effects may occur due to a dihydropyridine-type calcium channel
blocker?
1. Bradycardia
2. Hepatic impairment
3. Increased contractility
4. Edema of the hands and feet
____ 10. Patient teaching related to amlodipine includes:
1. Increase calcium intake to prevent osteoporosis from a calcium blockade.
2. Do not crush the tablet; it must be given in liquid form if the patient has trouble
swallowing it.
3. Avoid grapefruit juice as it affects the metabolism of this drug.
4. Rise slowly from a supine position to reduce orthostatic hypotension
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