NERVOUS SYSTEM
Benzodiazepines
• Alprazolam
• Diazepam
• Lorazepam
• Chlordiazepoxide
• Sedation
• Dependency/Withdrawal - Short term
• Antidote is Flumazenil
Atypical Anxiolytics
• Buspirone
• No Sedation - N
...
NERVOUS SYSTEM
Benzodiazepines
• Alprazolam
• Diazepam
• Lorazepam
• Chlordiazepoxide
• Sedation
• Dependency/Withdrawal - Short term
• Antidote is Flumazenil
Atypical Anxiolytics
• Buspirone
• No Sedation - No Dependency - Long term
• Full effects take weeks
• Take with meals
SSRIs
• Paroxetine
• Sertraline
• Fluoxetine
• Insomnia
• Watch for Serotonin Syndrome (Agitation, Hallucinations, Fever, Diaphoresis, Tremors)
• Do Not Take With St. John’s Wort
• Full Effects take months
Atypical Antidepressants
• Bupropion
• Trazodone (Major Side Effect - Sedation)
• Depression & Smoke Cessation
• Insomnia, headache, GI Distress, Weight Loss, Agitation, Seizures
TCAs
• Amitriptyline
• Imipramine
• Sedation, orthostatic hypotension Anticholinergic Effects (Urinary Retention, Constipation, Dry Mouth, Blurry Vision, Photophobia)
MAOIs
• Phenelzine
• Tranylcypromine
• HTN Crisis
• Do not eat foods with tyramine
Mood Stabilizers
• Lithium
• Side Effects: GI Upset, Fine Hand Tremors (Coarse in Tox), Polyuria, Weight gain, Kidney Tox, Electrolyte imbalances
• Monitor Plasma Levels: Tox over 1.5 mEq/L
• Toxicity (Coarse hand tremors, confusion, hypotension, seizures, tinnitus
• No diuretics, Anticholinergics or NSAIDs
• Contraindicated in Renal Disease
• Closely monitor NA, Drink 2-3 L of water
Antiepileptics (Bipolar Disorder)
• Carbamazepine (Blood Issues (Anemia, Thrombocytopenia & Leukopenia), Vision Issues & Rash)
• Valproic Acid (GI Upset, Hepatotoxicity, Pancreatitis, Thrombocytopenia)
Antipsychotics
• Chlorpromazine
• Haloperidol
• EPS, NMS, Agranulocytosis, Anticholinergic Effects, Sedation
....................................................................CONTINUED................................................................
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